Peptide Database

Peptide NameCalcitonin gene-related peptide

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC166H265N51O51S3

DescriptionStandard

        ACNTATCVTHRLADFLSRSGGMAKNNFVPTNVGSKAF
    

Molecular Weight3887.39 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)2.86

Net Charge (pH 7.4) 2.59

Charge Density (pH 7.0) 0.0774

GRAVY Index-0.03

Hydrophobic Moment 0.70

Boman Index0.04

Instability Index29.18

Aliphatic Index 58.11

Aromaticity 0.0811

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1657.92

LogP -23.02

H-bond Donors 60.0

H-bond Acceptors 58.0

Rotatable Bonds 125.0

Heavy Atoms 271.0

Ring Count 5.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0032815 VERIFIED: NO

Provenance & Taxonomy

OrganismRana ridibunda [Animal]

FamilyCalcitonin

Structure & Mods

Configlinear disulfide-stabilized peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide2-7

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0103826 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax ridibundus [Animal]

FamilyCalcitonin gene-related peptide (CGRP)

Tax ID8406

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide2-7

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasodilator

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0150972 VERIFIED: NO

Provenance & Taxonomy

OrganismRana ridibunda [Animal]

FamilyCalcitonin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0302419 VERIFIED: YES

Provenance & Taxonomy

OrganismNanorana parkeri [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)