Peptide Database

Peptide Namealpha-Glia AG11 (p78 p95; E86)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC93H135N21O26

DescriptionStandard

        PQPQPFLPELPYPQPQS
    

Molecular Weight1963.19 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.04

Net Charge (pH 7.4) -1.10

Charge Density (pH 7.0) -0.0612

GRAVY Index-1.20

Hydrophobic Moment 0.26

Boman Index0.01

Instability Index166.04

Aliphatic Index 45.88

Aromaticity 0.1176

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 712.31

LogP -5.18

H-bond Donors 19.0

H-bond Acceptors 25.0

Rotatable Bonds 51.0

Heavy Atoms 140.0

Ring Count 9.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0427306 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E86

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodT-cell proliferation assay