Peptide Database

Peptide Namecompound 2 [PMID: 11375253]

Function Ontology

Neurological / Signaling ▸ Neuropeptide activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC80H121N25O18S3

DescriptionStandard

        YGGRCMLGRVYRPCW
    

Molecular Weight1817.17 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)2.74

Net Charge (pH 7.4) 2.50

Charge Density (pH 7.0) 0.1826

GRAVY Index-0.33

Hydrophobic Moment 0.57

Boman Index-0.09

Instability Index40.93

Aliphatic Index 45.33

Aromaticity 0.2000

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 703.88

LogP -4.69

H-bond Donors 29.0

H-bond Acceptors 24.0

Rotatable Bonds 54.0

Heavy Atoms 126.0

Ring Count 5.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0280653 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsN-terminal tyrosine is iodinised

Bio-Activity Profile

Function

Receptor agonist Neuropeptide activity Signaling peptide

TargetMCH1 receptor (Human)