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MYP_008310
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Basic Information
Magainin-C2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
23 amino acids
C112H184N30O30S
Standard
Sequence
GVGKFLHSAKKFGQALVSEIMKS
Physicochemical Analysis
2462.91 Da
10.00
2.85
2.59
0.1237
0.10
0.64
0.12
18.93
84.78
0.0870
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
977.36
-8.72
34.0
35.0
87.0
173.0
3.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0029412 VERIFIED: YES
Provenance & Taxonomy
Xenopus clivii [Animal]
Magainin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
200.0 μM
HC50
PaperJ.M. Conlon et al. / Comparative Biochemistry and Physiology, Part C 153 (2011) 350-354. Purification and properties of antimicrobial peptides from skin secretions of the Eritrea clawed frog Xenopus clivii (Pipidae)
RECORD: Rec_0080723 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0183189 VERIFIED: YES
Provenance & Taxonomy
Xenopus clivii [Animal]
Magainin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
100.0 μM
MIC
PaperJ.M. Conlon et al. / Comparative Biochemistry and Physiology, Part C 153 (2011) 350-354. Purification and properties of antimicrobial peptides from skin secretions of the Eritrea clawed frog Xenopus clivii (Pipidae)
RECORD: Rec_0248398 VERIFIED: YES
Provenance & Taxonomy
Xenopus clivii [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial
PMID21199684 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21199684/
RECORD: Rec_0251885 VERIFIED: YES
Provenance & Taxonomy
Xenopus clivii [Animal]
Magainin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
50.0 μM
MIC
PaperJ.M. Conlon et al. / Comparative Biochemistry and Physiology, Part C 153 (2011) 350-354. Purification and properties of antimicrobial peptides from skin secretions of the Eritrea clawed frog Xenopus clivii (Pipidae)