Peptide Database

Peptide NameBeta-defensin 1 (BD-1) (sBD1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC313H525N107O75S8

DescriptionStandard

        MRLHHLLLVLFFVVLSAGSGFTQGVRNRLSCHRNKGVCVPSRCPRHMRQIGTCRGPPVKCCRKK
    

Molecular Weight7243.71 Da

Isoelectric Point (pI)11.49

Net Charge (pH 7.0)12.79

Net Charge (pH 7.4) 12.27

Charge Density (pH 7.0) 0.1998

GRAVY Index-0.11

Hydrophobic Moment 0.73

Boman Index-0.12

Instability Index41.34

Aliphatic Index 82.03

Aromaticity 0.0469

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2931.10

LogP -30.69

H-bond Donors 112.0

H-bond Acceptors 100.0

Rotatable Bonds 240.0

Heavy Atoms 503.0

Ring Count 11.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0186015 VERIFIED: YES

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyBeta-defensin; Defensin

Tax ID9940

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic

RECORD: Rec_0231014 VERIFIED: YES

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal