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MYP_008290
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Basic Information
Ranatuerin-1Ga
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
25 amino acids
C116H202N32O31S3
Standard
Sequence
SMISVLKNLGKVGLGFVACKVNKQC
Physicochemical Analysis
2637.24 Da
9.70
3.44
3.19
0.1375
0.61
0.57
0.18
26.11
112.80
0.0400
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1035.53
-9.87
37.0
38.0
93.0
182.0
1.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0014106 VERIFIED: YES
Provenance & Taxonomy
Rana grylio [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
9 μM
MIC
PMID10828493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10828493/
RECORD: Rec_0028998 VERIFIED: YES
Provenance & Taxonomy
Lithobates grylio [Animal]
Ranatuerin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
19-25
Bio-Activity Profile
Antimicrobial Antifungal
PaperJ.B. Kim et al. / Regulatory Peptides 90 (2000) 53-60. Purification and characterization of antimicrobial and vasorelaxant peptides from skin extracts and skin secretions of the North American pig frog Rana grylio
RECORD: Rec_0035530 VERIFIED: YES
Provenance & Taxonomy
American frog [Animal]
Ranatuerin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
19-25
Bio-Activity Profile
Antimicrobial
PMID10828493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10828493/
RECORD: Rec_0055487 VERIFIED: YES
Provenance & Taxonomy
Lithobates catesbeianus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0062012 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 32.0%, E 0.0%, T 40.0%, C 28.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
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