Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length447 amino acids

Chemical FormulaC2192H3522N586O623S21

DescriptionStandard

        MSLYCWLALVALVPMTLSTEPGVKVRITAKGLEYGRQVGMAALQEKLKAIRIPDFSGKQRVSRIGKVRYSLTNLIIKSVGLPTSSVNLVAGTGVKMSITGAFISVRGNWRVKYLFIRDSGSFDLDVRDLSISATIAIGRDATGHPMVSGANCAANVGSARVKFHGGASWLYNLFSKYINRALRKAMEKQICPLVTKAISDMNPRLQTLNVLAKVDKHAEIEYSMVSPPTISTSAIDLNLKGEFYNIGNHKEPPFSPKAISLPPQVNKMVYISLSAFTANSAGFVYNRAGILSEDITDDMVNYLPSDSTPKQVSCCVFQIARRFPGLMMKLVVKTAKDPIASFEPNSMTVNATGTVTAYAIQPNGALTSLFVLNLETSVSARVFLTGMRLGGAVTLNNFFDKIYEFCFIVQLAKGYPLPALKNMNLLNTQLQILKDNILIGTDVHFTG
    

Molecular Weight48726.33 Da

Isoelectric Point (pI)9.65

Net Charge (pH 7.0)18.89

Net Charge (pH 7.4) 18.24

Charge Density (pH 7.0) 0.0423

GRAVY Index0.15

Hydrophobic Moment 0.91

Boman Index0.12

Instability Index28.70

Aliphatic Index 98.81

Aromaticity 0.0828

Extinction Coeff. Reduced 37360.00

Extinction Coeff. Oxidized 37735.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0251138 VERIFIED: NO

Provenance & Taxonomy

OrganismSparus aurata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria