Peptide Database

Peptide NameSLAY-screened peptide P30

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC64H92N20O17

DescriptionStandard

        NLFPSHSATFRH
    

Molecular Weight1413.54 Da

Isoelectric Point (pI)9.76

Net Charge (pH 7.0)0.93

Net Charge (pH 7.4) 0.63

Charge Density (pH 7.0) 0.0779

GRAVY Index-0.59

Hydrophobic Moment 0.35

Boman Index-0.03

Instability Index67.60

Aliphatic Index 40.83

Aromaticity 0.1667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 597.67

LogP -6.78

H-bond Donors 21.0

H-bond Acceptors 20.0

Rotatable Bonds 41.0

Heavy Atoms 101.0

Ring Count 5.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0392671 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/