Peptide Database

Peptide NameMucroporin (Antimicrobial peptide 36.21) (Non-disulfide-bridged peptide 4.5) (NDBP-4.5)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Antibiotic activity

Antiviral

Antiviral ▸ Anti-HIV

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC396H636N110O99S4

DescriptionStandard

        MKVKFLLAVFLIVLVVTDHCHALFGLIPSLIGGLVSAFKGRRKRQMEARFEPQNRNYRKRELDLEKLFANMPDY
    

Molecular Weight8650.22 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)5.67

Net Charge (pH 7.4) 5.32

Charge Density (pH 7.0) 0.0766

GRAVY Index-0.00

Hydrophobic Moment 0.53

Boman Index-0.00

Instability Index38.66

Aliphatic Index 104.05

Aromaticity 0.1081

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3385.73

LogP -21.99

H-bond Donors 119.0

H-bond Acceptors 111.0

Rotatable Bonds 293.0

Heavy Atoms 609.0

Ring Count 13.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0036552 VERIFIED: YES

Provenance & Taxonomy

OrganismLychas mucronatus [Animal]

FamilyNDBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiviral Anti-HIV Anti-MRSA Anti-Hepatitis Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0065762 VERIFIED: YES

Provenance & Taxonomy

OrganismLychas mucronatus [Animal]

FamilyNDBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiviral Anti-HIV Anti-MRSA Anti-Hepatitis Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0101285 VERIFIED: YES

Provenance & Taxonomy

OrganismLychas mucronatus [Animal]

FamilyNDBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiviral Anti-HIV Anti-MRSA Anti-Hepatitis Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetBacillus subtilis (Gram-positive)

RECORD: Rec_0168498 VERIFIED: YES

Provenance & Taxonomy

OrganismLychas mucronatus [Animal]

FamilyNDBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiviral Anti-HIV Anti-MRSA Anti-Hepatitis Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetB. thuringiensis (Gram-positive)

RECORD: Rec_0403971 VERIFIED: YES

Provenance & Taxonomy

OrganismLychas mucronatus [Animal]

FamilyNDBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiviral Anti-HIV Anti-MRSA Anti-Hepatitis Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetPseudomonas aeruginosa (Gram-negative)