Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC553H880N146O168S3

DescriptionStandard

        PDLSGYEKYGLGNVKYNISRIHVTAVEFPSASISLIPGTGIKLVIGNASLTIDMNWNIRTWMFKDTGRSTVYISKVFVTAIFSTPLDNTGHTSLSLASCRTTSGDIDIKLNGKS
    

Molecular Weight12357.98 Da

Isoelectric Point (pI)9.20

Net Charge (pH 7.0)3.12

Net Charge (pH 7.4) 2.93

Charge Density (pH 7.0) 0.0274

GRAVY Index0.03

Hydrophobic Moment 0.53

Boman Index0.12

Instability Index10.91

Aliphatic Index 94.04

Aromaticity 0.0877

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 16960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5036.87

LogP -55.20

H-bond Donors 181.0

H-bond Acceptors 176.0

Rotatable Bonds 406.0

Heavy Atoms 870.0

Ring Count 18.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0046514 VERIFIED: NO

Provenance & Taxonomy

OrganismJacana jacana (Wattled jacana) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria