Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length228 amino acids

Chemical FormulaC1143H1769N267O340S9

DescriptionStandard

        IDDLAEVDYSLNGLPAVFRPFIDLDLKGTVYPAGKHTGLPYVAAPFTIPDQSNSMLYLAFSEYFFQTSSLAYYTAGAFNITIAEKTCSYFNISTEMFGSIIPEVAKYSVTPHPVMLKVMATEIPIISLEQDSFTAEIQGSMEVLAVLPDSTTQSLFTMNITANTSIALNIFDQKLMGSLCLNRLQFSLAHSNVGFFEISLLENVLSYILQTEVIPSANAKLSKGLPLP
    

Molecular Weight24979.44 Da

Isoelectric Point (pI)4.50

Net Charge (pH 7.0)-10.97

Net Charge (pH 7.4) -11.41

Charge Density (pH 7.0) -0.0481

GRAVY Index0.32

Hydrophobic Moment 0.60

Boman Index0.24

Instability Index40.22

Aliphatic Index 101.84

Aromaticity 0.1096

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0284908 VERIFIED: NO

Provenance & Taxonomy

OrganismTyto alba [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria