Peptide Database

Peptide NameLiraglutide

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC154H231N37O49

DescriptionStandard

        HAEGTFTSDVSSYLEGQAAKEEFIIAWLVKG
    

Molecular Weight3384.70 Da

Isoelectric Point (pI)4.57

Net Charge (pH 7.0)-3.14

Net Charge (pH 7.4) -3.41

Charge Density (pH 7.0) -0.1014

GRAVY Index-0.05

Hydrophobic Moment 0.37

Boman Index0.18

Instability Index27.96

Aliphatic Index 81.94

Aromaticity 0.1290

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1383.80

LogP -12.27

H-bond Donors 48.0

H-bond Acceptors 47.0

Rotatable Bonds 111.0

Heavy Atoms 240.0

Ring Count 6.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0205949 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGLP-1

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Other ModsAcylation of peptide at K-26 with C-18(palmitic acid) fatty di-acid chain

Bio-Activity Profile

Function

Insulin secretion stimulation

MethodELISA, LC/MS

Half-LifeRat Plasma (Dose i/v injected), in vivo; 51840 s