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MYP_008140
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Basic Information
Alyteserin-2a [S14K]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
16 amino acids
C75H137N19O20
Standard
Sequence
ILGKLLSTAAGLLKNL
Physicochemical Analysis
1625.01 Da
10.00
1.76
1.55
0.1099
1.08
0.48
0.37
5.49
183.12
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
635.41
-4.20
22.0
22.0
57.0
114.0
0.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0279139 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Toxic Drug Delivery Vehicle Cell-penetrating peptide Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0319271 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic
Human lung carcinoma A549
30 μM
LC50
PMID22965637;22392897 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22965637/
RECORD: Rec_0322050 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Stenotrophomonas maltophilia B32/4
64 μM
MIC
PMID22965637;22392897 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22965637/
RECORD: Rec_0346023 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 25923
16 μM
MIC
PMID22965637;22392897 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22965637/
RECORD: Rec_0367856 VERIFIED: YES
Provenance & Taxonomy
Alytes obstetricans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Cell-penetrating peptide
Human erythrocytes
55 μM
LC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/22965637/ PMID22965637 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22965637/
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