Peptide Database

Peptide NameHill-Def 7

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC169H281N51O53S7

DescriptionStandard

        TTCDLISGTKIENIACAAHCIAMGHKGGYCNSNLICICR
    

Molecular Weight4099.80 Da

Isoelectric Point (pI)7.54

Net Charge (pH 7.0)0.51

Net Charge (pH 7.4) 0.13

Charge Density (pH 7.0) 0.0132

GRAVY Index0.41

Hydrophobic Moment 0.44

Boman Index0.17

Instability Index46.83

Aliphatic Index 90.26

Aromaticity 0.0256

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1665.67

LogP -20.38

H-bond Donors 64.0

H-bond Acceptors 63.0

Rotatable Bonds 136.0

Heavy Atoms 280.0

Ring Count 3.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0321475 VERIFIED: YES

Provenance & Taxonomy

OrganismHermetia illucens [Animal]

FamilyDefensin

Tax ID343691

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetPseudomonas aeruginosa ATCC 9027

Activity32 μM

MethodIC50

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