Peptide Database

Peptide Name[I2] ascaphin-8

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC94H165N23O23

DescriptionStandard

        GIKDLLKGAAKALVKTVLF
    

Molecular Weight1985.46 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.1451

GRAVY Index0.83

Hydrophobic Moment 0.70

Boman Index0.25

Instability Index-14.38

Aliphatic Index 148.95

Aromaticity 0.0526

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 748.73

LogP -3.40

H-bond Donors 26.0

H-bond Acceptors 26.0

Rotatable Bonds 70.0

Heavy Atoms 140.0

Ring Count 1.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0164450 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAscaphin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

Target- Escherichia coli ATCC 25922

Activity3 μM

MethodMIC

RECORD: Rec_0198016 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAscaphin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targetrat RBCs

Activity142 μM

MethodHC50