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MYP_008091
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Basic Information
TPk (Derived from TP)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C94H140N30O14
Standard
Sequence
VRRPKWWWKFLRR
Physicochemical Analysis
1914.31 Da
12.00
5.73
5.52
0.4409
-1.48
0.63
-0.56
126.98
52.31
0.3077
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
750.74
-0.85
30.0
20.0
59.0
138.0
8.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0314903 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'k' in sequence is lysine peptoid residue [NH2-(CH2)4-NH-CH2-COOH]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
MRSA1 (CCARM 3001)
1 μM
MIC
PMID17604338 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17604338/
RECORD: Rec_0321917 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'k' in sequence is lysine peptoid residue [NH2-(CH2)4-NH-CH2-COOH]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID17604338 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17604338/
RECORD: Rec_0322636 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'k' in sequence is lysine peptoid residue [NH2-(CH2)4-NH-CH2-COOH]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
PMID17604338 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17604338/
RECORD: Rec_0366019 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'k' in sequence is lysine peptoid residue [NH2-(CH2)4-NH-CH2-COOH]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
MDRPA2 (CCARM 2109)
8 μM
MIC
PMID17604338 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17604338/
RECORD: Rec_0382286 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
Nlys [NH2 –(CH2)4 –NH–CH2 –COOH].
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus
1 μM
MIC
PMID17604338 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17604338/
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