Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length242 amino acids

Chemical FormulaC1261H1901N277O362S8

DescriptionStandard

        IDDLAEVDYSLNSLPAVFRPFIDLDLKGIVYPAGNYTGPPYVAAPIIIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEEVINSFIFFFFFFLQTCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPIISLEQDSFTVEIQGSMEVFAVLPDSTTQSLFTMNIVTNTSIALNIFDQKLMGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight26989.74 Da

Isoelectric Point (pI)4.09

Net Charge (pH 7.0)-15.14

Net Charge (pH 7.4) -15.48

Charge Density (pH 7.0) -0.0626

GRAVY Index0.48

Hydrophobic Moment 0.60

Boman Index0.30

Instability Index44.11

Aliphatic Index 104.38

Aromaticity 0.1488

Extinction Coeff. Reduced 17880.00

Extinction Coeff. Oxidized 18005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0106053 VERIFIED: NO

Provenance & Taxonomy

OrganismPodiceps cristatus [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria