Peptide Database

Peptide NameGlia-alpha2 25-mer (p64p89; E65 and E79)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC144H203N31O38

DescriptionStandard

        PELPQFLQPQPYPQPELPYPQPQPF
    

Molecular Weight2976.34 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.04

Net Charge (pH 7.4) -2.10

Charge Density (pH 7.0) -0.0815

GRAVY Index-1.18

Hydrophobic Moment 0.28

Boman Index0.03

Instability Index143.55

Aliphatic Index 46.80

Aromaticity 0.1600

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1042.22

LogP -5.14

H-bond Donors 27.0

H-bond Acceptors 36.0

Rotatable Bonds 78.0

Heavy Atoms 213.0

Ring Count 14.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0160479 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E65; Reported substitutions/positions: E79

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodT-cell proliferation assay