Peptide Database

Peptide Namebeta-Theraphotoxin-Cm2a

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC185H277N53O56S6

DescriptionStandard

        GVDKEGCRKLLGGCTIDDDCCPHLGCNKKYWHCGWDGTF
    

Molecular Weight4331.89 Da

Isoelectric Point (pI)6.02

Net Charge (pH 7.0)-1.12

Net Charge (pH 7.4) -1.53

Charge Density (pH 7.0) -0.0288

GRAVY Index-0.56

Hydrophobic Moment 0.49

Boman Index-0.04

Instability Index31.63

Aliphatic Index 47.44

Aromaticity 0.1026

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1742.83

LogP -17.61

H-bond Donors 66.0

H-bond Acceptors 63.0

Rotatable Bonds 140.0

Heavy Atoms 300.0

Ring Count 9.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0082140 VERIFIED: NO

Provenance & Taxonomy

OrganismCeratogyrus marshalli [Animal]; Ceratogyrus cornuatus [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide7-21; 14-26; 20-33

Bio-Activity Profile

Function

Toxin

TargetNav1