Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC393H610N106O106S12

DescriptionStandard

        MTLSRKMSSFVFAFFILAQFLSGCQAGLEYSEPLPGGEFSPCEPCWLGRGKCRRMCTEDEKVIGQCRMNFFCCRPKIK
    

Molecular Weight8900.47 Da

Isoelectric Point (pI)8.71

Net Charge (pH 7.0)3.43

Net Charge (pH 7.4) 3.08

Charge Density (pH 7.0) 0.0440

GRAVY Index-0.05

Hydrophobic Moment 0.57

Boman Index0.02

Instability Index54.19

Aliphatic Index 56.28

Aromaticity 0.1282

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3392.89

LogP -30.19

H-bond Donors 126.0

H-bond Acceptors 122.0

Rotatable Bonds 293.0

Heavy Atoms 617.0

Ring Count 16.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0247543 VERIFIED: NO

Provenance & Taxonomy

OrganismEnhydra lutris kenyoni [Bacterium]

FamilyDefensin

Tax ID391180

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence