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MYP_007898
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Basic Information
Temporin-1Ga
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C76H123N15O19
Standard
Sequence
SILPTIVSFLSKVF
Physicochemical Analysis
1550.88 Da
8.47
0.46
0.25
0.0328
1.57
0.52
0.53
24.67
152.86
0.1429
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
539.77
-2.32
19.0
20.0
48.0
110.0
3.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0062786 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0090600 VERIFIED: YES
Provenance & Taxonomy
American frog [Animal]
Temporin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID11892844 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11892844/
RECORD: Rec_0092430 VERIFIED: YES
Provenance & Taxonomy
Rana grylio [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis 168
6.3 μM
MIC
PMID10828493;29842923 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10828493/
RECORD: Rec_0096938 VERIFIED: YES
Provenance & Taxonomy
Rana grylio [Animal]
Temporin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPubMed PMID: 10828493 PMID10828493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10828493/
RECORD: Rec_0099536 VERIFIED: YES
Provenance & Taxonomy
Rana grylio [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
C-terminal amidation
Bio-Activity Profile
Antimicrobial Antifungal
Bacillus subtilis 168
6.2 μM
MIC
PaperPurification and characterization of antimicrobial and vasorelaxant peptides from skin extracts and skin secretions of the North American pig frog Rana grylio
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