Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC147H228N42O46S

DescriptionStandard

        NTVTCATQRLANFLIHSSNNFGAIFSPPSVGS
    

Molecular Weight3351.70 Da

Isoelectric Point (pI)8.26

Net Charge (pH 7.0)0.84

Net Charge (pH 7.4) 0.57

Charge Density (pH 7.0) 0.0262

GRAVY Index0.19

Hydrophobic Moment 0.48

Boman Index0.19

Instability Index22.97

Aliphatic Index 76.25

Aromaticity 0.0938

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1415.71

LogP -19.98

H-bond Donors 49.0

H-bond Acceptors 49.0

Rotatable Bonds 103.0

Heavy Atoms 236.0

Ring Count 6.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0311755 VERIFIED: YES

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)