Peptide Database

Peptide NameTyr0α-CGRP (human)

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC172H277N51O52S2

DescriptionStandard

        YACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF
    

Molecular Weight3955.48 Da

Isoelectric Point (pI)9.39

Net Charge (pH 7.0)2.83

Net Charge (pH 7.4) 2.54

Charge Density (pH 7.0) 0.0744

GRAVY Index0.17

Hydrophobic Moment 0.59

Boman Index0.10

Instability Index38.47

Aliphatic Index 79.47

Aromaticity 0.0789

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1664.16

LogP -21.49

H-bond Donors 61.0

H-bond Acceptors 58.0

Rotatable Bonds 126.0

Heavy Atoms 277.0

Ring Count 5.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0219972 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Vasoactive Signaling peptide

TargetAMY1 receptor (Human); AMY2 receptor (Human)