Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length482 amino acids

Chemical FormulaC2425H3836N620O680S14

DescriptionStandard

        MARGPDSVQRWATLVALAALGTAVTTTNPGIVARVTQKGLDYACQQGVLTLQKELEKITIPTFSGSFKIKYLGKGQYSFFSMVIGGFSLPNSQIRPLPGEGLDLSIRDASIKIRGKWKARKNFIKLSGNFDLSVEGISILAGLNLGYDPDSGHSTVTCSSCSSHINTVRIRISGSSLGWLIQLFHKRIESSLQKSMTSKICEVVTSTVSSKLQPYFQTLPVTTKLDKVAGVDYSLVAPPRATTDNLDGLLKGEFFSLAHRSPPPFAPPALAFPTDHDRMVFLGISEYFFNTAGFVYQKAGALNLTLRDDMIPKESKFHLTTKFFGTVIPQVAKRFPDMQMQLFIWASLPPKLSVNPSGLDLIFVLDTQAFAILPNSSLDPLFLLEMNLNLSVVVGAKSDRLTGELRLDKLLLELKHSDIGPFSVELLQSAMNYVLPTVVLPMINKKLQKGFPLPLPANIELFNLILQPYQDFLLFGADVHYS
    

Molecular Weight53005.05 Da

Isoelectric Point (pI)9.19

Net Charge (pH 7.0)9.18

Net Charge (pH 7.4) 8.40

Charge Density (pH 7.0) 0.0191

GRAVY Index0.12

Hydrophobic Moment 0.71

Boman Index0.14

Instability Index33.86

Aliphatic Index 101.54

Aromaticity 0.0934

Extinction Coeff. Reduced 38390.00

Extinction Coeff. Oxidized 38640.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0254206 VERIFIED: NO

Provenance & Taxonomy

OrganismMoschus moschiferus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence