Peptide Database

Peptide NameProenkephalin-A [209-230]

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC109H161N23O43S

DescriptionStandard

        FAEPLPSEEEGESYSKEVPEME
    

Molecular Weight2513.64 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-7.21

Net Charge (pH 7.4) -7.44

Charge Density (pH 7.0) -0.3279

GRAVY Index-1.20

Hydrophobic Moment 0.43

Boman Index-0.10

Instability Index96.18

Aliphatic Index 35.45

Aromaticity 0.0909

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1053.39

LogP -9.58

H-bond Donors 33.0

H-bond Acceptors 37.0

Rotatable Bonds 81.0

Heavy Atoms 176.0

Ring Count 5.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0085955 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0374100 VERIFIED: NO