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MYP_007777
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Basic Information
Japonicin-2 (Frogs, amphibians, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
21 amino acids
C110H193N27O23S3
Standard
Sequence
FGLPMLSILPKALCILLKRKC
Physicochemical Analysis
2358.07 Da
9.85
3.74
3.50
0.1780
1.08
0.52
0.27
54.10
153.33
0.0476
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
787.93
-1.38
29.0
30.0
79.0
163.0
3.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0345407 VERIFIED: NO
Provenance & Taxonomy
Rana japonica [Animal]
Structure & Mods
disulfide-stabilized linear peptide [Linear]
canonical L-amino-acid peptide [L]
14-21
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli; Staphylococcus aureus
RECORD: Rec_0383902 VERIFIED: YES
Provenance & Taxonomy
Rana japonica [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
12 μM
MIC
PMID11835990 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11835990/
RECORD: Rec_0419311 VERIFIED: YES
Provenance & Taxonomy
Rana japonica [Animal]
Structure & Mods
disulfide-stabilized linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
14-21
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
12 μM
MIC
PMID11835990 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11835990/
RECORD: Rec_0426287 VERIFIED: YES
Provenance & Taxonomy
Rana japonica [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
14-21
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus
20 μM
MIC
PaperAntimicrobial peptides with atypical structural features from the skin of the Japanese brown frog Rana japonica. PMID11835990
RECORD: Rec_0427155 VERIFIED: NO
Provenance & Taxonomy
Rana japonica [Animal]
Japonicin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
14-21
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli; Staphylococcus aureus
MIC
PaperT. Isaacson et al. / Peptides 23 (2002) 419-425. Antimicrobial peptides with atypical structural features from the skin of the Japanese brown frog Rana japonica PMID11835990 Evidence URLhttps://www.uniprot.org/uniprotkb/E3WH22/entry
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