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MYP_007777
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Basic Information
Japonicin-2 (Frogs, amphibians, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
21 amino acids
C110H193N27O23S3
Standard
Sequence
FGLPMLSILPKALCILLKRKC
Physicochemical Analysis
2358.07 Da
9.85
3.74
3.50
0.1780
1.08
0.52
0.27
54.10
153.33
0.0476
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
787.93
-1.38
29.0
30.0
79.0
163.0
3.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0187256 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 38.1%, E 0.0%, T 28.6%, C 33.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0229561 VERIFIED: NO
Provenance & Taxonomy
Japanese reddish [Animal]
Japonicin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0249369 VERIFIED: YES
Provenance & Taxonomy
Rana japonica [Animal]
Japonicin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
14-21
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
20.0 μM
MIC
PaperT. Isaacson et al. / Peptides 23 (2002) 419-425. Antimicrobial peptides with atypical structural features from the skin of the Japanese brown frog Rana japonica Evidence URLhttps://www.uniprot.org/uniprotkb/P83306/entry
RECORD: Rec_0269340 VERIFIED: YES
Provenance & Taxonomy
Rana japonica [Animal]
Japonicin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
14-21
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
12.0 μM
MIC
PaperT. Isaacson et al. / Peptides 23 (2002) 419-425. Antimicrobial peptides with atypical structural features from the skin of the Japanese brown frog Rana japonica Evidence URLhttps://www.uniprot.org/uniprotkb/P83306/entry
RECORD: Rec_0322119 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
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