Peptide Database

Peptide NameFlounder beta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC169H281N45O62S6

DescriptionStandard

        PKADCSTIQGVCKDSCLSTEFSIGALGCSAESSTVCCVTKP
    

Molecular Weight4127.69 Da

Isoelectric Point (pI)4.78

Net Charge (pH 7.0)-1.10

Net Charge (pH 7.4) -1.25

Charge Density (pH 7.0) -0.0267

GRAVY Index0.25

Hydrophobic Moment 0.36

Boman Index0.11

Instability Index31.30

Aliphatic Index 66.59

Aromaticity 0.0244

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1697.42

LogP -25.55

H-bond Donors 66.0

H-bond Acceptors 67.0

Rotatable Bonds 135.0

Heavy Atoms 282.0

Ring Count 3.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0007506 VERIFIED: YES

Provenance & Taxonomy

OrganismParalichthys olivaceus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus

Activity8.11-16.22 μg/mL

MethodMIC

RECORD: Rec_0033966 VERIFIED: YES

Provenance & Taxonomy

OrganismParalichthys olivaceus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetMicrococcus luteus

Activity4.06-8.11 μg/mL

MethodMIC

RECORD: Rec_0102183 VERIFIED: YES

Provenance & Taxonomy

OrganismParalichthys olivaceus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetV. alginolyticus

Activity2.03-4.06 μg/mL

MethodMIC

RECORD: Rec_0329549 VERIFIED: YES

Provenance & Taxonomy

OrganismParalichthys olivaceus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

Activity406-8.11 μg/mL

MethodMIC

RECORD: Rec_0384865 VERIFIED: YES

Provenance & Taxonomy

OrganismParalichthys olivaceus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetV. anguillarum

Activity2.03-4.06 μg/mL

MethodMIC