Peptide Database

Peptide Namegamma5 (p66-p77; E68, E71 and E76)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC68H93N15O23

DescriptionStandard

        FPEQPEQPYPEQ
    

Molecular Weight1488.55 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-3.23

Net Charge (pH 7.4) -3.44

Charge Density (pH 7.0) -0.2694

GRAVY Index-2.16

Hydrophobic Moment 0.31

Boman Index-0.24

Instability Index159.20

Aliphatic Index 0.00

Aromaticity 0.1667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 609.66

LogP -4.66

H-bond Donors 16.0

H-bond Acceptors 20.0

Rotatable Bonds 41.0

Heavy Atoms 106.0

Ring Count 6.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0031526 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E68,E71; Reported substitutions/positions: E76

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodT-cell proliferation assay