Peptide Database

Peptide NameSLAY-screened peptide P713

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC54H75N11O15

DescriptionStandard

        PLTDWWTSL
    

Molecular Weight1118.24 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.04

Net Charge (pH 7.4) -1.10

Charge Density (pH 7.0) -0.1156

GRAVY Index-0.17

Hydrophobic Moment 0.45

Boman Index0.30

Instability Index-7.81

Aliphatic Index 86.67

Aromaticity 0.2222

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 411.70

LogP -1.53

H-bond Donors 16.0

H-bond Acceptors 14.0

Rotatable Bonds 30.0

Heavy Atoms 80.0

Ring Count 5.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0085780 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/