Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length100 amino acids

Chemical FormulaC522H857N147O143S8

DescriptionStandard

        MKLLLIIAILLLQKSKVTEQLKRCWGEYIHGYCRKICRISEIRQVLCENGRYCCLNIVELEARRKITKPPPPKPRTYAMTFPQDEDIPIENYSRPKANST
    

Molecular Weight11736.81 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)7.54

Net Charge (pH 7.4) 7.15

Charge Density (pH 7.0) 0.0754

GRAVY Index-0.41

Hydrophobic Moment 0.77

Boman Index-0.12

Instability Index53.49

Aliphatic Index 94.60

Aromaticity 0.0700

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4710.59

LogP -38.05

H-bond Donors 169.0

H-bond Acceptors 160.0

Rotatable Bonds 393.0

Heavy Atoms 820.0

Ring Count 17.0

Amide Bonds 107.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0023876 VERIFIED: NO

Provenance & Taxonomy

OrganismLeptonychotes weddellii [Animal]

FamilyDefensin

Tax ID9713

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0226318 VERIFIED: NO