Peptide Database

Peptide NameSLAY-screened peptide P1923

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC63H75N13O17S

DescriptionStandard

        DGYYFWHIDC
    

Molecular Weight1318.41 Da

Isoelectric Point (pI)4.20

Net Charge (pH 7.0)-2.16

Net Charge (pH 7.4) -2.43

Charge Density (pH 7.0) -0.2162

GRAVY Index-0.43

Hydrophobic Moment 0.05

Boman Index0.25

Instability Index80.47

Aliphatic Index 39.00

Aromaticity 0.4000

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 484.75

LogP -0.85

H-bond Donors 18.0

H-bond Acceptors 17.0

Rotatable Bonds 36.0

Heavy Atoms 94.0

Ring Count 6.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0291236 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/