Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length208 amino acids

Chemical FormulaC1068H1615N241O312S6

DescriptionStandard

        QGIVYPAGNYTGSPYVAAPFTIPDQSDSMLYLAFSEHFFQTSSFAYYTAGAFNITIAEEVKSGKILYFYFFLQTCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPIISLEQDSFTAEIQGSMEVFAVLPDSTTQLLFTLNIAANTSIALNIFDQKLVGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVIPSANGK
    

Molecular Weight23015.06 Da

Isoelectric Point (pI)4.40

Net Charge (pH 7.0)-10.06

Net Charge (pH 7.4) -10.45

Charge Density (pH 7.0) -0.0484

GRAVY Index0.39

Hydrophobic Moment 0.55

Boman Index0.28

Instability Index47.17

Aliphatic Index 100.38

Aromaticity 0.1442

Extinction Coeff. Reduced 17880.00

Extinction Coeff. Oxidized 18005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0219677 VERIFIED: NO

Provenance & Taxonomy

OrganismBurhinus bistriatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria