Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC170H273N49O56S2

DescriptionStandard

        KCNTATCVTQRLADFLVRSSNSIGAIYPPTNVGSNTY
    

Molecular Weight3963.41 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0470

GRAVY Index-0.13

Hydrophobic Moment 0.68

Boman Index0.03

Instability Index11.41

Aliphatic Index 73.78

Aromaticity 0.0811

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1718.44

LogP -23.89

H-bond Donors 62.0

H-bond Acceptors 60.0

Rotatable Bonds 124.0

Heavy Atoms 277.0

Ring Count 5.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0023339 VERIFIED: YES

Provenance & Taxonomy

OrganismCuculus canorus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)