Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length286 amino acids

Chemical FormulaC1468H2302N360O397S12

DescriptionStandard

        MEDICKMLTNTVSSKLQPYFQTLPVTAKVDRMVGINYSLVAPPKATAENLDGLLKGEFFSLDHPSPPPFAPPALALPADHDRMVYLCISEYFFNTAGLVYQKAGVLNLTINNSMIPKKSLFSLTTNFFGTLIPKVSTMFPNMEMQFLIWASFPPHLAVHPSGLDLTFVLETQAFAVLPNASLAPLFLIEMNSSISVDIGVRSKRLIGELRLNKLLLELKHSNIGPFSVELLQAVMNFAVPTLVLPKINEKLQRGFPLPLPAYIQLSNLVLQPHQDFLLFGADVRYS
    

Molecular Weight31730.93 Da

Isoelectric Point (pI)7.01

Net Charge (pH 7.0)0.02

Net Charge (pH 7.4) -0.58

Charge Density (pH 7.0) 0.0001

GRAVY Index0.28

Hydrophobic Moment 0.69

Boman Index0.21

Instability Index34.48

Aliphatic Index 107.73

Aromaticity 0.0979

Extinction Coeff. Reduced 15930.00

Extinction Coeff. Oxidized 16055.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0174179 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence