Peptide Database

Peptide NameGastrin-releasing peptide

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC81H132N22O22

DescriptionStandard

        APLQPGGSPALTKIYPR
    

Molecular Weight1766.05 Da

Isoelectric Point (pI)9.99

Net Charge (pH 7.0)1.79

Net Charge (pH 7.4) 1.60

Charge Density (pH 7.0) 0.1055

GRAVY Index-0.36

Hydrophobic Moment 0.42

Boman Index0.08

Instability Index93.51

Aliphatic Index 80.59

Aromaticity 0.0588

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 685.46

LogP -6.40

H-bond Donors 22.0

H-bond Acceptors 24.0

Rotatable Bonds 50.0

Heavy Atoms 125.0

Ring Count 5.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0030057 VERIFIED: YES

Provenance & Taxonomy

OrganismCoturnix japonica [Animal]

FamilyGastrin-releasing peptide

Tax ID93934

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0217704 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0386451 VERIFIED: YES

Provenance & Taxonomy

OrganismCoturnix coturnix japonica [Animal]

FamilyBombesin/neuromedin-B/ranatensin

Tax ID93934

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Hormone