Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length536 amino acids

Chemical FormulaC2656H4226N718O728S14

DescriptionStandard

        MDRALQKQTGVGGGGTLLRWPGKPFGGSVACCVPHSLASRLAARAPSPRLQHDRSVSEIQGPLVQRGSQLPSPGAAWMSHQSRWIGLHRAAALVLKATARQEGITALQKELAKLKLPDFSGTFKVKLLGKVHYTFYSLNLRSFQLPSSQIAPIPNVGLKVSIANAFAQLTGKWRVKKRFIRDSGSFDLKVEGLSISIGLKLGSDASGRPTVTTSECGTHISNVRVHISGRFGWLYNLFHKKIESSFRKTMEGKVCGVVTSSVTTKLQPYLQTVPVTAKIDKVAGIDYSLVAPPAATAQSLDVNLKGEFFSLAHRSAVPFPPPALAFPVDHDRMVYCGASSYFFNTAGFVYHTAGALLFEITDAMIPKEFKFHLNTTTFSAFIPQLEKMYPDKLMKLRIKTSSAPFLTITPGNLSLTPVVDIQAYVILPNSSLVSVFLLSVTSSVSAKIMVTSARIGGTLELGRLQLSLKHSDVGPFSVQLLQALMNFYGSSILIPRINARLKEGFPLPLPARVQLSSLVIQPHQNFLLFGADVRYV
    

Molecular Weight58313.25 Da

Isoelectric Point (pI)10.08

Net Charge (pH 7.0)30.68

Net Charge (pH 7.4) 29.59

Charge Density (pH 7.0) 0.0572

GRAVY Index0.11

Hydrophobic Moment 0.74

Boman Index0.12

Instability Index43.55

Aliphatic Index 97.15

Aromaticity 0.0877

Extinction Coeff. Reduced 45380.00

Extinction Coeff. Oxidized 45630.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0302566 VERIFIED: NO

Provenance & Taxonomy

OrganismChrysemys picta bellii (Western painted turtle) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria