Peptide Database

Peptide NameCXCL12

Function Ontology

Immunology ▸ Immune cell migration ▸ Chemotactic peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC380H628N114O97S5

DescriptionStandard

        KPVSLSYRCPCRFFESHIARANVKHLKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKALNKRLKM
    

Molecular Weight8506.08 Da

Isoelectric Point (pI)10.11

Net Charge (pH 7.0)10.89

Net Charge (pH 7.4) 10.51

Charge Density (pH 7.0) 0.1513

GRAVY Index-0.42

Hydrophobic Moment 0.63

Boman Index-0.16

Instability Index33.16

Aliphatic Index 98.89

Aromaticity 0.0694

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3474.47

LogP -29.19

H-bond Donors 123.0

H-bond Acceptors 115.0

Rotatable Bonds 290.0

Heavy Atoms 596.0

Ring Count 12.0

Amide Bonds 81.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0322142 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Chemotactic Immunomodulatory Signaling peptide

TargetCXCR4 (Mouse)