Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length50 amino acids

Chemical FormulaC221H346N64O70S7

DescriptionStandard

        CPGDAHGPDSCNHRGGLCRVGACVSGEYLAQFCFEPVILCCKNLSLATTE
    

Molecular Weight5243.95 Da

Isoelectric Point (pI)5.48

Net Charge (pH 7.0)-2.12

Net Charge (pH 7.4) -2.54

Charge Density (pH 7.0) -0.0424

GRAVY Index0.14

Hydrophobic Moment 0.38

Boman Index0.12

Instability Index35.79

Aliphatic Index 72.20

Aromaticity 0.0600

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2107.18

LogP -25.39

H-bond Donors 78.0

H-bond Acceptors 77.0

Rotatable Bonds 165.0

Heavy Atoms 362.0

Ring Count 8.0

Amide Bonds 52.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0353014 VERIFIED: YES

Provenance & Taxonomy

OrganismSylvia borin [Animal]

FamilyDefensin

Tax ID73324

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

PaperLocus-specific protocol for nine different innate immune genes (antimicrobial peptides: β-defensins) across passerine bird species reveals within-species coding variation and a case of trans-species polymorphisms [PMID:21676198] PMID21676198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21676198/