Peptide Database

Peptide NameLyP-1

Function Ontology

Anticancer

Anticancer ▸ Tumor Homing Peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC37H69N17O12S2

DescriptionStandard

        CGQKRTRGC
    

Molecular Weight1008.18 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)2.74

Net Charge (pH 7.4) 2.51

Charge Density (pH 7.0) 0.3044

GRAVY Index-1.43

Hydrophobic Moment 0.30

Boman Index-0.66

Instability Index35.68

Aliphatic Index 0.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 509.26

LogP -8.30

H-bond Donors 21.0

H-bond Acceptors 17.0

Rotatable Bonds 35.0

Heavy Atoms 68.0

Ring Count 0.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0131090 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide1-9

Bio-Activity Profile

Function

Tumor homing Anticancer Cytotoxic p32/gC1qR-binding Drug delivery vehicle

TargetMDA-MB-435 tumor cells; tumor lymphatics

Methodtumor-homing/binding assay; LDH cytotoxicity assay

RECORD: Rec_0414894 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Anticancer