Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC318H545N99O98S8

DescriptionStandard

        MEAQLITVTSLLLVRSDLEVNRICGYGTARCRRKCKEQEKKIGRCPNTSDCCLKTWSESVLRTMKQ
    

Molecular Weight7579.85 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)5.45

Net Charge (pH 7.4) 5.13

Charge Density (pH 7.0) 0.0826

GRAVY Index-0.47

Hydrophobic Moment 0.61

Boman Index-0.22

Instability Index37.91

Aliphatic Index 79.70

Aromaticity 0.0303

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3270.55

LogP -37.12

H-bond Donors 124.0

H-bond Acceptors 112.0

Rotatable Bonds 265.0

Heavy Atoms 523.0

Ring Count 4.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0273103 VERIFIED: NO

Provenance & Taxonomy

OrganismCastor canadensis [Animal]

FamilyDefensin

Tax ID51338

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal