Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC915H1384N214O281S10

DescriptionStandard

        IDDLAKIDYSLNNFPAVSQPFIDLDLKGTVYPSGNHTGPSCVAAPFVIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNINTEIFGSIIPEVREYSVTPYPVMLKLMATEMPIISLQQDSFTAEIQGSMEVFAVLPDSTTQSLFTMNVAANTSIAPNIFDHKLMGSLCLNR
    

Molecular Weight20198.69 Da

Isoelectric Point (pI)4.11

Net Charge (pH 7.0)-13.07

Net Charge (pH 7.4) -13.46

Charge Density (pH 7.0) -0.0714

GRAVY Index0.19

Hydrophobic Moment 0.51

Boman Index0.22

Instability Index50.47

Aliphatic Index 85.85

Aromaticity 0.1257

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7830.17

LogP -86.07

H-bond Donors 265.0

H-bond Acceptors 280.0

Rotatable Bonds 640.0

Heavy Atoms 1420.0

Ring Count 37.0

Amide Bonds 199.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0265182 VERIFIED: NO

Provenance & Taxonomy

OrganismIndicator maculatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria