Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length483 amino acids

Chemical FormulaC2381H3781N615O680S17

DescriptionStandard

        MARGPDNTPRWAALMVLAALGTAVTETTNPGIVARITQKGLDYARQQGVATLQKELGKMEIPSFSGSFKVKFLGKGEYSFYSLVIREVQLPSSQIRLLPSEGLALSVTDASVKISGKWKARKNFIKTSGNFDLSVEGVSISAGLNLSCDPASGHSTVTCSGCSNHIDSIHVHVSGSHLGWLIQLFHKKIESSLQKALNDKICQVVTKSVSSKLKPFFQTMPVTAKIDNVAGIDYSLLAPPTATTETLDGQLKGEFFSLAHRSPPPFAPPALAIPMDHDHMVYLGISDYFFNTAGLVYQQAGVLNLTLKDDMIPKKSKFRLTTKYFGTLIPQLAKMFPNMSMQFLIRVSSPPHLTVSPAGLACTPVLEAQAFAVLPNSSLAPLFLLGMSSNASVEVGAVSDRLVGELSLDKLLLELKHSDIGPFSVELLQAIMNYIVPTTVLPKVNERLQKGYPLPLPTHVQLFNLVLQSYQNFLLFGADVLYN
    

Molecular Weight52447.31 Da

Isoelectric Point (pI)8.97

Net Charge (pH 7.0)7.52

Net Charge (pH 7.4) 6.52

Charge Density (pH 7.0) 0.0156

GRAVY Index0.13

Hydrophobic Moment 0.72

Boman Index0.15

Instability Index35.84

Aliphatic Index 99.92

Aromaticity 0.0807

Extinction Coeff. Reduced 34380.00

Extinction Coeff. Oxidized 34630.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0126604 VERIFIED: NO

Provenance & Taxonomy

OrganismMyotis myotis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria