Peptide Database

Peptide NameSLAY-screened peptide P3208

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC114H175N31O26S3

DescriptionStandard

        VYCLRCLFRFYSCQLKSPHK
    

Molecular Weight2492.00 Da

Isoelectric Point (pI)9.42

Net Charge (pH 7.0)3.79

Net Charge (pH 7.4) 3.48

Charge Density (pH 7.0) 0.1894

GRAVY Index-0.03

Hydrophobic Moment 0.65

Boman Index-0.08

Instability Index93.02

Aliphatic Index 73.00

Aromaticity 0.2000

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 935.96

LogP -5.92

H-bond Donors 37.0

H-bond Acceptors 34.0

Rotatable Bonds 79.0

Heavy Atoms 174.0

Ring Count 6.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0314227 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/