Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC363H555N91O90S8

DescriptionStandard

        MKPFLVTLAVLLLFFQVTPGSIEKCWNFRGSCRDECLKNEKVYVFCMSGKLCCLKPKDQPHLPHEWW
    

Molecular Weight7890.37 Da

Isoelectric Point (pI)8.60

Net Charge (pH 7.0)2.62

Net Charge (pH 7.4) 2.20

Charge Density (pH 7.0) 0.0391

GRAVY Index-0.01

Hydrophobic Moment 0.36

Boman Index0.08

Instability Index39.88

Aliphatic Index 81.34

Aromaticity 0.1343

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 18365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2868.18

LogP -16.21

H-bond Donors 103.0

H-bond Acceptors 103.0

Rotatable Bonds 254.0

Heavy Atoms 552.0

Ring Count 19.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0028119 VERIFIED: NO

Provenance & Taxonomy

OrganismTheropithecus gelada [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence