Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC404H633N101O134S12

DescriptionStandard

        MKTLSVAVAVVVLTFINIQESSAFPVTGVQQPEETMSLDDPSAEEEETSVETWMMPYNIGQKNYSDPVRCQFCCGCCVPGVCGTCCV
    

Molecular Weight9433.72 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-8.56

Net Charge (pH 7.4) -8.91

Charge Density (pH 7.0) -0.0984

GRAVY Index0.16

Hydrophobic Moment 0.51

Boman Index0.15

Instability Index64.90

Aliphatic Index 71.49

Aromaticity 0.0690

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3721.61

LogP -41.26

H-bond Donors 131.0

H-bond Acceptors 138.0

Rotatable Bonds 300.0

Heavy Atoms 651.0

Ring Count 13.0

Amide Bonds 94.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0176917 VERIFIED: NO

Provenance & Taxonomy

OrganismSeriola dumerili [Bacterium]

FamilyHepcidin family

Tax ID41447

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic

MethodQualitative functional evidence