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MYP_007364
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Basic Information
CP11CN
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
13 amino acids
C96H138N26O14
Standard
Sequence
ILKKWPWWPWRRK
Physicochemical Analysis
1880.29 Da
12.00
4.76
4.55
0.3659
-1.48
0.48
-0.28
57.15
60.00
0.3077
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
659.96
2.13
25.0
19.0
55.0
136.0
10.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0303150 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 23.1%, C 76.9% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0303438 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Indolicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa
16 μg/mL
MIC
Trypsin: Half-life is 18 min
PaperRozek A, Powers JP, Friedrich CL, Hancock RE. Structure-based design of an indolicidin peptide analogue with increased protease stability. Biochemistry. 2003 Dec 9;42(48):14130-8. PMID:14640680 https://pubmed.ncbi.nlm.nih.gov/14640680/ PMID14640680 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14640680/
RECORD: Rec_0308862 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus haemolyticus
2 μg/mL
MIC
PMID11473117 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11473117/
RECORD: Rec_0333078 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus ATCC 25923
16 μg/mL
MIC
PaperPubMed PMID: 11294848 PMID11294848 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11294848/
RECORD: Rec_0333851 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus
16 μg/mL
MIC
PMID11473117 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11473117/
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