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MYP_007364
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Basic Information
CP11CN
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
13 amino acids
C96H138N26O14
Standard
Sequence
ILKKWPWWPWRRK
Physicochemical Analysis
1880.29 Da
12.00
4.76
4.55
0.3659
-1.48
0.48
-0.28
57.15
60.00
0.3077
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
659.96
2.13
25.0
19.0
55.0
136.0
10.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0177099 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus haemolyticus
1 μg/mL
MIC
PMID11473117 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11473117/
RECORD: Rec_0188476 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis
64 μg/mL
MIC
PMID11473117 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11473117/
RECORD: Rec_0203494 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Indolicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus epidermidis
4 μg/mL
MIC
Trypsin: Half-life is 18 min
PaperRozek A, Powers JP, Friedrich CL, Hancock RE. Structure-based design of an indolicidin peptide analogue with increased protease stability. Biochemistry. 2003 Dec 9;42(48):14130-8. PMID:14640680 https://pubmed.ncbi.nlm.nih.gov/14640680/ PMID14640680 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14640680/
RECORD: Rec_0206934 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
aureus SAP0017 MRSA
16 μg/mL
MIC
PaperPubMed PMID: 11294848 PMID11294848 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11294848/
RECORD: Rec_0212221 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Listeria monocytogenes NCTC 7973
16 μg/mL
MIC
PaperPubMed PMID: 11294848 PMID11294848 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11294848/
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