Peptide Database

Peptide NameP12G-pleurain-A1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC133H222N36O37S3

DescriptionStandard

        SIITMTKEAKLGQLWKQIACRLYNTC
    

Molecular Weight3013.60 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)2.44

Net Charge (pH 7.4) 2.20

Charge Density (pH 7.0) 0.0938

GRAVY Index-0.01

Hydrophobic Moment 0.56

Boman Index0.03

Instability Index37.08

Aliphatic Index 97.69

Aromaticity 0.0769

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1214.29

LogP -10.19

H-bond Donors 45.0

H-bond Acceptors 43.0

Rotatable Bonds 103.0

Heavy Atoms 209.0

Ring Count 3.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0074360 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

Activity120 μg/mL

MethodMIC

RECORD: Rec_0162752 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetCandida albicans

Activity60 μg/mL

MethodMIC

RECORD: Rec_0248135 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetBacillus subtilis

Activity120 μg/mL

MethodMIC

RECORD: Rec_0327773 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus

Activity15 μg/mL

MethodMIC