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MYP_007304
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Basic Information
Lantibiotic Nisin-A
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
34 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
IXXIXLXXPGXKXGALMGXNMKXAXXHXSIHVXK
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0227763 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis subsp. lactis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,3,5,7,8,11,13,19,23,25,26,28,33
Bio-Activity Profile
Antimicrobial Antibacterial
Mycobacterium kansasii CIT11/06
60 μg/mL
MIC90
PMID19506061;12540174;23571533;33346078;20547041;33398076 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19506061/
RECORD: Rec_0242406 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis subsp. lactis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,3,5,7,8,11,13,19,23,25,26,28,33
Bio-Activity Profile
Antimicrobial Antibacterial
Lactococcus lactis HP ATCC 11602 IC90
0.019 μM
PMID19506061;12540174;23571533;33346078;20547041;33398076 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19506061/
RECORD: Rec_0252130 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis subsp. lactis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,3,5,7,8,11,13,19,23,25,26,28,33
Bio-Activity Profile
Antimicrobial Antibacterial
Latilactobacillus sakei subsp. sakei JCM 1157
0.008 μM
MIC
PMID19506061;12540174;23571533;33346078;20547041;33398076 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19506061/
RECORD: Rec_0256852 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis subsp. lactis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,3,5,7,8,11,13,19,23,25,26,28,33
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa
128 μg/mL
MIC
PMID19506061;12540174;23571533;33346078;20547041;33398076 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19506061/
RECORD: Rec_0303403 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis subsp. lactis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,3,5,7,8,11,13,19,23,25,26,28,33
Bio-Activity Profile
Hemolytic
human red blood cells
6.58±1.87 % hemolysis at 4000 μg/mL
Hemolysis
PMID19506061;12540174;23571533;33346078;20547041;33398076 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19506061/
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